Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways

Pioglitazone hydrochloride (PGZ), a nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, is a universally adopted oral agent for the treatment of type 2 diabetes (T2D). Previous studies reported that PGZ could ameliorate the symptoms of aging-related diseases and Alzhe...

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Detalles Bibliográficos
Autores principales: Jia, Wenjuan, Wang, Chongyang, Zheng, Jingming, Li, Yimin, Yang, Caixian, Wan, Qin-Li, Shen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168093/
https://www.ncbi.nlm.nih.gov/pubmed/35677109
http://dx.doi.org/10.1155/2022/8496063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168093/
https://www.ncbi.nlm.nih.gov/pubmed/35677109
http://dx.doi.org/10.1155/2022/8496063

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