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Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways

Pioglitazone hydrochloride (PGZ), a nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, is a universally adopted oral agent for the treatment of type 2 diabetes (T2D). Previous studies reported that PGZ could ameliorate the symptoms of aging-related diseases and Alzhe...

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Detalles Bibliográficos
Autores principales:	Jia, Wenjuan, Wang, Chongyang, Zheng, Jingming, Li, Yimin, Yang, Caixian, Wan, Qin-Li, Shen, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168093/ https://www.ncbi.nlm.nih.gov/pubmed/35677109 http://dx.doi.org/10.1155/2022/8496063

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