Impact of APOE ε4 Carrier Status on Associations Between Subthreshold, Positive Amyloid-β Deposition, Brain Function, and Cognitive Performance in Cognitively Normal Older Adults: A Prospective Study

BACKGROUND: A growing body of evidence suggests a deteriorating effect of subthreshold amyloid-beta (Aβ) accumulation on cognition before the onset of clinical symptoms of Alzheimer's disease (AD). Despite the association between the Aβ-dependent pathway and the APOE ε4 allele, the impact of th...

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Detalles Bibliográficos
Autores principales: Kang, Dong Woo, Wang, Sheng-Min, Um, Yoo Hyun, Kim, Nak-Young, Lee, Chang Uk, Lim, Hyun Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168227/
https://www.ncbi.nlm.nih.gov/pubmed/35677201
http://dx.doi.org/10.3389/fnagi.2022.871323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168227/
https://www.ncbi.nlm.nih.gov/pubmed/35677201
http://dx.doi.org/10.3389/fnagi.2022.871323

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