Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

Allogeneic hematopoietic cell transplantation (Allo-HCT) is a curative therapy for hematological malignancies (i.e., leukemia and lymphoma) due to the graft-versus-leukemia (GVL) activity mediated by alloreactive T cells that can eliminate residual malignant cells and prevent relapse. However, the s...

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Detalles Bibliográficos
Autores principales: Song, Qingxiao, Nasri, Ubaydah, Nakamura, Ryotaro, Martin, Paul J., Zeng, Defu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168269/
https://www.ncbi.nlm.nih.gov/pubmed/35677056
http://dx.doi.org/10.3389/fimmu.2022.907673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168269/
https://www.ncbi.nlm.nih.gov/pubmed/35677056
http://dx.doi.org/10.3389/fimmu.2022.907673

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