CD38-Induced Apoptosis and Mitochondrial Damage is Restored by Nicotinamide in Prostate Cancer

Nicotinamide adenine dinucleotide (NAD(+)) is an essential molecule for living organisms. CD38 is a key NAD(+)-dependent enzyme which breaks down NAD(+) to cyclic ADP-ribose (ADPR) and nicotinamide (NAM, vitamin B3), and NAM can be recycled to synthesize NAD(+). CD38 expression is consistently silen...

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Detalles Bibliográficos
Autores principales: Kanayama, Mayuko, Luo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168365/
https://www.ncbi.nlm.nih.gov/pubmed/35677882
http://dx.doi.org/10.3389/fmolb.2022.890402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168365/
https://www.ncbi.nlm.nih.gov/pubmed/35677882
http://dx.doi.org/10.3389/fmolb.2022.890402

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