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CD38-Induced Apoptosis and Mitochondrial Damage is Restored by Nicotinamide in Prostate Cancer
Nicotinamide adenine dinucleotide (NAD(+)) is an essential molecule for living organisms. CD38 is a key NAD(+)-dependent enzyme which breaks down NAD(+) to cyclic ADP-ribose (ADPR) and nicotinamide (NAM, vitamin B3), and NAM can be recycled to synthesize NAD(+). CD38 expression is consistently silen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168365/ https://www.ncbi.nlm.nih.gov/pubmed/35677882 http://dx.doi.org/10.3389/fmolb.2022.890402 |