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Leaky gut model of the human intestinal mucosa for testing siRNA-based nanomedicine targeting JAK1

Complex in vitro models of human immune cells and intestinal mucosa may have a translation-assisting role in the assessment of anti-inflammatory compounds. Chronic inflammation of the gastrointestinal tract is a hallmark of inflammatory bowel diseases (IBD). In both IBD entities, Crohn's diseas...

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Detalles Bibliográficos
Autores principales: Hartwig, Olga, Loretz, Brigitta, Nougarede, Adrien, Jary, Dorothée, Sulpice, Eric, Gidrol, Xavier, Navarro, Fabrice, Lehr, Claus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168449/
https://www.ncbi.nlm.nih.gov/pubmed/35339579
http://dx.doi.org/10.1016/j.jconrel.2022.03.037