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Leaky gut model of the human intestinal mucosa for testing siRNA-based nanomedicine targeting JAK1
Complex in vitro models of human immune cells and intestinal mucosa may have a translation-assisting role in the assessment of anti-inflammatory compounds. Chronic inflammation of the gastrointestinal tract is a hallmark of inflammatory bowel diseases (IBD). In both IBD entities, Crohn's diseas...
Autores principales: | Hartwig, Olga, Loretz, Brigitta, Nougarede, Adrien, Jary, Dorothée, Sulpice, Eric, Gidrol, Xavier, Navarro, Fabrice, Lehr, Claus-Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168449/ https://www.ncbi.nlm.nih.gov/pubmed/35339579 http://dx.doi.org/10.1016/j.jconrel.2022.03.037 |
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