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Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix–loop–helix-mediated dimer formation

Persistence of Acinetobacter baumannii in environments with low water activity is largely attributed to the biosynthesis of compatible solutes. Mannitol is one of the key compatible solutes in A. baumannii, and it is synthesized by a bifunctional mannitol-1-phosphate dehydrogenase/phosphatase (AbMtl...

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Detalles Bibliográficos
Autores principales: Tam, Heng-Keat, König, Patricia, Himpich, Stephanie, Ngu, Ngoc Dinh, Abele, Rupert, Müller, Volker, Pos, Klaas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168451/
https://www.ncbi.nlm.nih.gov/pubmed/35363566
http://dx.doi.org/10.1073/pnas.2107994119