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Carbon sources and pathways for citrate secreted by human prostate cancer cells determined by NMR tracing and metabolic modeling

Prostate epithelial cells have the unique capacity to secrete large amounts of citrate, but the carbon sources and metabolic pathways that maintain this production are not well known. We mapped potential pathways for citrate carbons in the human prostate cancer metastasis cell lines LNCaP and VCaP,...

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Detalles Bibliográficos
Autores principales: van Heijster, Frits H. A., Breukels, Vincent, Jansen, Kees (C.) F. J., Schalken, Jack A., Heerschap, Arend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168453/
https://www.ncbi.nlm.nih.gov/pubmed/35353621
http://dx.doi.org/10.1073/pnas.2024357119