Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

Aspergillus fumigatus is the causative agent of invasive aspergillosis, an infection with mortality rates of up to 50%. The glucan-rich cell wall of A. fumigatus is a protective structure that is absent from human cells and is a potential target for antifungal treatments. Glucan is synthesized from...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Kaizhou, Stanley, Mathew, Kowalski, Bartosz, Raimi, Olawale G., Ferenbach, Andrew T., Wei, Pingzhen, Fang, Wenxia, van Aalten, Daan M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168620/
https://www.ncbi.nlm.nih.gov/pubmed/35504355
http://dx.doi.org/10.1016/j.jbc.2022.102003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168620/
https://www.ncbi.nlm.nih.gov/pubmed/35504355
http://dx.doi.org/10.1016/j.jbc.2022.102003

Ejemplares similares