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Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma

Efficacy of immunotherapy in hepatocellular carcinoma (HCC) is blocked by its high degree of inter‐ and intra‐tumor heterogeneity and immunosuppressive tumor microenvironment. However, the correlation between tumor heterogeneity and immunosuppressive microenvironment in HCC has not been well address...

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Detalles Bibliográficos
Autores principales: Wang, Tingjie, Dang, Ningxin, Tang, Guangbo, Li, Zihang, Li, Xiujuan, Shi, Bingyin, Xu, Zhong, Li, Lei, Yang, Xiaofei, Xu, Chuanrui, Ye, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168757/
https://www.ncbi.nlm.nih.gov/pubmed/35124891
http://dx.doi.org/10.1002/1878-0261.13190