Targeting Stress Sensor Kinases in Hepatocellular Carcinoma-Infiltrating Human NK Cells as a Novel Immunotherapeutic Strategy for Liver Cancer

Natural killer (NK) cells may become functionally exhausted entering hepatocellular carcinoma (HCC), and this has been associated with tumor progression and poor clinical outcome. Hypoxia, low nutrients, immunosuppressive cells, and soluble mediators characterize the intratumor microenvironment resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zecca, Alessandra, Barili, Valeria, Olivani, Andrea, Biasini, Elisabetta, Boni, Carolina, Fisicaro, Paola, Montali, Ilaria, Tiezzi, Camilla, Dalla Valle, Raffaele, Ferrari, Carlo, Cariani, Elisabetta, Missale, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168800/
https://www.ncbi.nlm.nih.gov/pubmed/35677052
http://dx.doi.org/10.3389/fimmu.2022.875072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168800/
https://www.ncbi.nlm.nih.gov/pubmed/35677052
http://dx.doi.org/10.3389/fimmu.2022.875072

Ejemplares similares