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Targeting Stress Sensor Kinases in Hepatocellular Carcinoma-Infiltrating Human NK Cells as a Novel Immunotherapeutic Strategy for Liver Cancer
Natural killer (NK) cells may become functionally exhausted entering hepatocellular carcinoma (HCC), and this has been associated with tumor progression and poor clinical outcome. Hypoxia, low nutrients, immunosuppressive cells, and soluble mediators characterize the intratumor microenvironment resp...
Autores principales: | Zecca, Alessandra, Barili, Valeria, Olivani, Andrea, Biasini, Elisabetta, Boni, Carolina, Fisicaro, Paola, Montali, Ilaria, Tiezzi, Camilla, Dalla Valle, Raffaele, Ferrari, Carlo, Cariani, Elisabetta, Missale, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168800/ https://www.ncbi.nlm.nih.gov/pubmed/35677052 http://dx.doi.org/10.3389/fimmu.2022.875072 |
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