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Clamping of DNA shuts the condensin neck gate

Condensin is a structural maintenance of chromosomes (SMC) complex needed for the compaction of DNA into chromatids during mitosis. Lengthwise DNA compaction by condensin is facilitated by ATPase-driven loop extrusion, a process that is believed to be the fundamental activity of most, if not all, SM...

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Detalles Bibliográficos
Autores principales: Lee, Byung-Gil, Rhodes, James, Löwe, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168836/
https://www.ncbi.nlm.nih.gov/pubmed/35349345
http://dx.doi.org/10.1073/pnas.2120006119