Protective role of chaperone-mediated autophagy against atherosclerosis

Chaperone-mediated autophagy (CMA) contributes to regulation of energy homeostasis by timely degradation of enzymes involved in glucose and lipid metabolism. Here, we report reduced CMA activity in vascular smooth muscle cells and macrophages in murine and human arteries in response to atherosclerot...

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Detalles Bibliográficos
Autores principales: Madrigal-Matute, Julio, de Bruijn, Jenny, van Kuijk, Kim, Riascos-Bernal, Dario F., Diaz, Antonio, Tasset, Inmaculada, Martín-Segura, Adrián, Gijbels, Marion J. J., Sander, Bianca, Kaushik, Susmita, Biessen, Erik A. L., Tiano, Simoni, Bourdenx, Mathieu, Krause, Gregory J., McCracken, Ian, Baker, Andrew H., Jin, Han, Sibinga, Nicholas E. S., Bravo-Cordero, Jose Javier, Macian, Fernando, Singh, Rajat, Rensen, Patrick C. N., Berbée, Jimmy F. P., Pasterkamp, Gerard, Sluimer, Judith C., Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168839/
https://www.ncbi.nlm.nih.gov/pubmed/35363568
http://dx.doi.org/10.1073/pnas.2121133119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168839/
https://www.ncbi.nlm.nih.gov/pubmed/35363568
http://dx.doi.org/10.1073/pnas.2121133119

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