Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy

Demyelination is a pathological feature of diabetic neuropathy, a common and painful complication of diabetes, yet the mechanisms underlying diabetes-induced demyelination remain unclear. Here, we show that targeting mixed lineage kinase domain–like protein (MLKL), a protein critical in necroptosis,...

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Detalles Bibliográficos
Autores principales: Guo, Jia, Guo, Zehui, Huang, Yanju, Ma, Suchen, Yan, Bo, Pan, Chenjie, Jiang, Zhaodi, Wang, Fengchao, Zhang, Zhiyuan, Da, Yuwei, Wang, Xiaodong, Ying, Zhengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168919/
https://www.ncbi.nlm.nih.gov/pubmed/35344427
http://dx.doi.org/10.1073/pnas.2121552119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168919/
https://www.ncbi.nlm.nih.gov/pubmed/35344427
http://dx.doi.org/10.1073/pnas.2121552119

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