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Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy
Demyelination is a pathological feature of diabetic neuropathy, a common and painful complication of diabetes, yet the mechanisms underlying diabetes-induced demyelination remain unclear. Here, we show that targeting mixed lineage kinase domain–like protein (MLKL), a protein critical in necroptosis,...
Autores principales: | Guo, Jia, Guo, Zehui, Huang, Yanju, Ma, Suchen, Yan, Bo, Pan, Chenjie, Jiang, Zhaodi, Wang, Fengchao, Zhang, Zhiyuan, Da, Yuwei, Wang, Xiaodong, Ying, Zhengxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168919/ https://www.ncbi.nlm.nih.gov/pubmed/35344427 http://dx.doi.org/10.1073/pnas.2121552119 |
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