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Histone methylation-mediated microRNA-32-5p down-regulation in sensory neurons regulates pain behaviors via targeting Cav3.2 channels

microRNA (miRNA)–mediated gene regulation has been studied as a therapeutic approach, but its functional regulatory mechanism in neuropathic pain is not well understood. Here, we identify that miRNA-32-5p (miR-32-5p) is a functional RNA in regulating trigeminal-mediated neuropathic pain. High-throug...

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Detalles Bibliográficos
Autores principales: Qi, Renfei, Cao, Junping, Sun, Yufang, Li, Yanping, Huang, Zitong, Jiang, Dongsheng, Jiang, Xing-Hong, Snutch, Terrance P., Zhang, Yuan, Tao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9168926/
https://www.ncbi.nlm.nih.gov/pubmed/35353623
http://dx.doi.org/10.1073/pnas.2117209119