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Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways

[Image: see text] Human immunodeficiency virus 1 (HIV-1) infects blood monocytes that cross the blood–brain barrier to the central nervous system, inducing neuronal damage. This is prompted by the secretion of viral and neurotoxic factors by HIV-infected macrophages, resulting in HIV-associated neur...

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Detalles Bibliográficos
Autores principales: Zenón-Meléndez, Camille N., Carrasquillo Carrión, Kelvin, Cantres Rosario, Yadira, Roche Lima, Abiel, Meléndez, Loyda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169015/
https://www.ncbi.nlm.nih.gov/pubmed/34994563
http://dx.doi.org/10.1021/acs.jproteome.1c00187