STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway

Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear. Here, we identified that STAT6 acted as a critical regulator of epithelium ferroptosis during ALI. Firstly, STAT6 expression and activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Youjing, Ma, Yu, Li, Qianmin, Ling, Yi, Zhou, Yujia, Chu, Kaimiao, Xue, Lian, Tao, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169029/
https://www.ncbi.nlm.nih.gov/pubmed/35668064
http://dx.doi.org/10.1038/s41419-022-04971-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169029/
https://www.ncbi.nlm.nih.gov/pubmed/35668064
http://dx.doi.org/10.1038/s41419-022-04971-x

Ejemplares similares