Cargando…

STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway

Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear. Here, we identified that STAT6 acted as a critical regulator of epithelium ferroptosis during ALI. Firstly, STAT6 expression and activity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Youjing, Ma, Yu, Li, Qianmin, Ling, Yi, Zhou, Yujia, Chu, Kaimiao, Xue, Lian, Tao, Shasha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169029/ https://www.ncbi.nlm.nih.gov/pubmed/35668064 http://dx.doi.org/10.1038/s41419-022-04971-x

Ejemplares similares

STAT6/VDR Axis Mitigates Lung Inflammatory Injury by Promoting Nrf2 Signaling Pathway
por: Yang, Youjing, et al.
Publicado: (2022)

STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation
por: Li, Jianzhong, et al.
Publicado: (2022)

Nrf2 and STAT3 Alleviates Ferroptosis-Mediated IIR-ALI by Regulating SLC7A11
por: Qiang, Zhuanzhuan, et al.
Publicado: (2020)

Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells
por: Luo, Yi, et al.
Publicado: (2021)

Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis
por: Huang, Yue-bo, et al.
Publicado: (2022)

Arbutin alleviates fatty liver by inhibiting ferroptosis via FTO/SLC7A11 pathway
por: Jiang, Tianyu, et al.
Publicado: (2023)

CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer
por: Zhang, Xiaoqian, et al.
Publicado: (2023)

Bixin Protects Against Kidney Interstitial Fibrosis Through Promoting STAT6 Degradation
por: Li, Jianzhong, et al.
Publicado: (2020)

Corrigendum: Bixin Protects Against Kidney Interstitial Fibrosis Through Promoting STAT6 Degradation
por: Li, Jianzhong, et al.
Publicado: (2021)

Quercetin ameliorates ferroptosis of rat cardiomyocytes via activation of the SIRT1/p53/SLC7A11 signaling pathway to alleviate sepsis-induced cardiomyopathy
por: Lin, Xin, et al.
Publicado: (2023)

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis
por: Yang, Youjing, et al.
Publicado: (2023)

HSDL2 knockdown promotes the progression of cholangiocarcinoma by inhibiting ferroptosis through the P53/SLC7A11 axis
por: Ma, Shuoshuo, et al.
Publicado: (2023)

Resveratrol Alleviates Diabetic Periodontitis-Induced Alveolar Osteocyte Ferroptosis Possibly via Regulation of SLC7A11/GPX4
por: Li, Yue, et al.
Publicado: (2023)

Tanshinone IIA induces ferroptosis in gastric cancer cells through p53-mediated SLC7A11 down-regulation
por: Guan, Zhenhua, et al.
Publicado: (2020)

SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling
por: Zeng, Chong, et al.
Publicado: (2022)

Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer
por: Yang, Jingjing, et al.
Publicado: (2021)

SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
por: Lee, Jaewang, et al.
Publicado: (2022)

Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11
por: Dong, Hui, et al.
Publicado: (2021)

PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer
por: Hong, Ting, et al.
Publicado: (2021)

Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis
por: Qi, Debin, et al.
Publicado: (2022)

Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis
por: Shao, Sisi, et al.
Publicado: (2023)

Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway
por: Jin, Xiaoming, et al.
Publicado: (2023)

TXNDC12 knockdown promotes ferroptosis by modulating SLC7A11 expression in glioma
por: Yu, Hao, et al.
Publicado: (2023)

miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes
por: Chen, Yongquan, et al.
Publicado: (2023)

The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi‐omics study
por: Xu, Fangshi, et al.
Publicado: (2021)

The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells
por: Zhang, Zili, et al.
Publicado: (2020)

Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11
por: Wang, Yishu, et al.
Publicado: (2020)

SLC7A11, a Potential Therapeutic Target Through Induced Ferroptosis in Colon Adenocarcinoma
por: Cheng, Xin, et al.
Publicado: (2022)

LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination
por: Zhang, Baofu, et al.
Publicado: (2022)

ATF3 promotes ferroptosis in sorafenib-induced cardiotoxicity by suppressing Slc7a11 expression
por: Li, Yilan, et al.
Publicado: (2022)

PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer
por: Shen, Liliang, et al.
Publicado: (2022)

Capsaicin induces ferroptosis of NSCLC by regulating SLC7A11/GPX4 signaling in vitro
por: Liu, Xiao-Yan, et al.
Publicado: (2022)

SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma
por: Chen, Qianping, et al.
Publicado: (2022)

HBx facilitates ferroptosis in acute liver failure via EZH2 mediated SLC7A11 suppression
por: Liu, Guo-Zhen, et al.
Publicado: (2021)

METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m(6)A modification
por: Xu, Yiming, et al.
Publicado: (2022)

Rotavirus-induced lncRNA SLC7A11-AS1 promotes ferroptosis by targeting cystine/glutamate antiporter xCT (SLC7A11) to facilitate virus infection
por: Banerjee, Shreya, et al.
Publicado: (2023)

SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma
por: Huang, Chao-Yuan, et al.
Publicado: (2022)

Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
por: Sehm, Tina, et al.
Publicado: (2016)

SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production
por: Zhao, Xiaohuan, et al.
Publicado: (2021)

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
por: Koppula, Pranavi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9bvulesmj4sd33s2qguohhanuk