Cargando…

Thermoadaptation in an Ancestral Diterpene Cyclase by Altered Loop Stability

[Image: see text] Thermostability is the key to maintain the structural integrity and catalytic activity of enzymes in industrial biotechnological processes, such as terpene cyclase-mediated generation of medicines, chiral synthons, and fine chemicals. However, affording a large increase in the ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Hueting, David A., Vanga, Sudarsana R., Syrén, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169049/
https://www.ncbi.nlm.nih.gov/pubmed/35583961
http://dx.doi.org/10.1021/acs.jpcb.1c10605