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Thermoadaptation in an Ancestral Diterpene Cyclase by Altered Loop Stability
[Image: see text] Thermostability is the key to maintain the structural integrity and catalytic activity of enzymes in industrial biotechnological processes, such as terpene cyclase-mediated generation of medicines, chiral synthons, and fine chemicals. However, affording a large increase in the ther...
Autores principales: | Hueting, David A., Vanga, Sudarsana R., Syrén, Per-Olof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169049/ https://www.ncbi.nlm.nih.gov/pubmed/35583961 http://dx.doi.org/10.1021/acs.jpcb.1c10605 |
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