Human cytomegalovirus lytic infection inhibits replication-dependent histone synthesis and requires stem loop binding protein function

Replication-dependent (RD) histones are deposited onto human cytomegalovirus (HCMV) genomes at the start of infection. We examined how HCMV affects the de novo production of RD histones and found that viral infection blocked the accumulation of RD histone mRNAs that normally occurs during the S phas...

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Detalles Bibliográficos
Autores principales: Albright, Emily R., Morrison, Kylee, Ranganathan, Padhma, Carter, Dominique M., Nishikiori, Masaki, Lee, Jeong-Hee, Slayton, Mark D., Ahlquist, Paul, Terhune, Scott S., Kalejta, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169081/
https://www.ncbi.nlm.nih.gov/pubmed/35344424
http://dx.doi.org/10.1073/pnas.2122174119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169081/
https://www.ncbi.nlm.nih.gov/pubmed/35344424
http://dx.doi.org/10.1073/pnas.2122174119

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