Inositol hexakisphosphate kinase-2 non-catalytically regulates mitophagy by attenuating PINK1 signaling

Inositol pyrophosphates, such as 5-diphosphoinositol pentakisphosphate (IP(7)), are generated by a family of inositol hexakisphosphate kinases (IP6Ks), of which IP6K2 has been implicated in various cellular functions including neuroprotection. Absence of IP6K2 causes impairment of oxidative phosphor...

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Detalles Bibliográficos
Autores principales: Nagpal, Latika, Kornberg, Michael D., Snyder, Solomon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169102/
https://www.ncbi.nlm.nih.gov/pubmed/35353626
http://dx.doi.org/10.1073/pnas.2121946119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169102/
https://www.ncbi.nlm.nih.gov/pubmed/35353626
http://dx.doi.org/10.1073/pnas.2121946119

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