Let-7 underlies metformin-induced inhibition of hepatic glucose production

Metformin, the frontline antidiabetic drug, has gained increasing attention for the prevention and treatment of aging, cancer, and cardiovascular disease. Yet a clear mechanistic understanding of its action is still lacking, largely due to the suprapharmacological concentrations of metformin used in...

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Detalles Bibliográficos
Autores principales: Xie, Di, Chen, Fan, Zhang, Yuanyuan, Shi, Bei, Song, Jiahui, Chaudhari, Kiran, Yang, Shao-Hua, Zhang, Gary J., Sun, Xiaoli, Taylor, Hugh S., Li, Da, Huang, Yingqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169108/
https://www.ncbi.nlm.nih.gov/pubmed/35344434
http://dx.doi.org/10.1073/pnas.2122217119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169108/
https://www.ncbi.nlm.nih.gov/pubmed/35344434
http://dx.doi.org/10.1073/pnas.2122217119

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