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Let-7 underlies metformin-induced inhibition of hepatic glucose production
Metformin, the frontline antidiabetic drug, has gained increasing attention for the prevention and treatment of aging, cancer, and cardiovascular disease. Yet a clear mechanistic understanding of its action is still lacking, largely due to the suprapharmacological concentrations of metformin used in...
Autores principales: | Xie, Di, Chen, Fan, Zhang, Yuanyuan, Shi, Bei, Song, Jiahui, Chaudhari, Kiran, Yang, Shao-Hua, Zhang, Gary J., Sun, Xiaoli, Taylor, Hugh S., Li, Da, Huang, Yingqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169108/ https://www.ncbi.nlm.nih.gov/pubmed/35344434 http://dx.doi.org/10.1073/pnas.2122217119 |
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