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Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation

Osteoblast dysfunction, induced by high glucose (HG), negatively impacts bone homeostasis and contributes to the pathology of diabetic osteoporosis (DOP). One of the most widely recognized mechanisms for osteoblast dysfunction is oxidative stress. Resveratrol (RES) is a bioactive antioxidant compoun...

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Detalles Bibliográficos
Autores principales: Xuan, Yue, Wang, Jie, Zhang, Xiaohui, Li, Jiahao, Liu, Qingbo, Lu, Guangping, Xiao, Mengjie, Gao, Ting, Guo, Yuanfang, Cao, Cong, Chen, Ou, Wang, Kunli, Tang, Yufeng, Gu, Junlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169221/
https://www.ncbi.nlm.nih.gov/pubmed/35677434
http://dx.doi.org/10.3389/fphar.2022.862618