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Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation
Osteoblast dysfunction, induced by high glucose (HG), negatively impacts bone homeostasis and contributes to the pathology of diabetic osteoporosis (DOP). One of the most widely recognized mechanisms for osteoblast dysfunction is oxidative stress. Resveratrol (RES) is a bioactive antioxidant compoun...
Autores principales: | Xuan, Yue, Wang, Jie, Zhang, Xiaohui, Li, Jiahao, Liu, Qingbo, Lu, Guangping, Xiao, Mengjie, Gao, Ting, Guo, Yuanfang, Cao, Cong, Chen, Ou, Wang, Kunli, Tang, Yufeng, Gu, Junlian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169221/ https://www.ncbi.nlm.nih.gov/pubmed/35677434 http://dx.doi.org/10.3389/fphar.2022.862618 |
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