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Trypanosoma cruzi iron superoxide dismutases: insights from phylogenetics to chemotherapeutic target assessment

BACKGROUND: Components of the antioxidant defense system in Trypanosoma cruzi are potential targets for new drug development. Superoxide dismutases (SODs) constitute key components of antioxidant defense systems, removing excess superoxide anions by converting them into oxygen and hydrogen peroxide....

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Detalles Bibliográficos
Autores principales: Hickson, Jéssica, Athayde, Lucas Felipe Almeida, Miranda, Thainá Godinho, Junior, Policarpo Ademar Sales, dos Santos, Anderson Coqueiro, da Cunha Galvão, Lúcia Maria, da Câmara, Antônia Cláudia Jácome, Bartholomeu, Daniella Castanheira, de Souza, Rita de Cássia Moreira, Murta, Silvane Maria Fonseca, Nahum, Laila Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169349/
https://www.ncbi.nlm.nih.gov/pubmed/35668508
http://dx.doi.org/10.1186/s13071-022-05319-2