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Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition

Background and Purpose: Myocardial infarction (MI) in diabetic patients results in higher mortality and morbidity. We and others have previously shown that bone marrow-endothelial progenitor cells (EPCs) promote cardiac neovascularization and attenuate ischemic injury. Lately, small extracellular ve...

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Detalles Bibliográficos
Autores principales: Huang, Grace, Cheng, Zhongjian, Hildebrand, Alycia, Wang, Chunlin, Cimini, Maria, Roy, Rajika, Lucchese, Anna Maria, Benedict, Cindy, Mallaredy, Vandana, Magadum, Ajit, Joladarashi, Darukeshwara, Thej, Charan, Gonzalez, Carolina, Trungcao, May, Garikipati, Venkata Naga Srikanth, Elrod, John W., Koch, Walter J., Kishore, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169353/
https://www.ncbi.nlm.nih.gov/pubmed/35673580
http://dx.doi.org/10.7150/thno.70821