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TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling

Rationale: In the glioblastoma (GBM) microenvironment, tumor-associated macrophages (TAMs) are prominent components and facilitate tumor growth. The exact molecular mechanisms underlying TAMs' function in promoting glioma stem cells (GSCs) maintenance and tumor growth remain largely unknown. We...

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Detalles Bibliográficos
Autores principales: Peng, Peng, Zhu, Hongtao, Liu, Dan, Chen, Zirong, Zhang, Xiaolin, Guo, Zhongyin, Dong, Minhai, Wan, Lijun, Zhang, Po, Liu, Guohao, Zhang, Suojun, Dong, Fangyong, Hu, Feng, Cheng, Fangling, Huang, Shijun, Guo, Dongsheng, Zhang, Bin, Yu, Xingjiang, Wan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169371/
https://www.ncbi.nlm.nih.gov/pubmed/35673564
http://dx.doi.org/10.7150/thno.69605