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Exosomal EPHA2 derived from highly metastatic breast cancer cells promotes angiogenesis by activating the AMPK signaling pathway through Ephrin A1-EPHA2 forward signaling

Rationale: Angiogenesis is a fundamental process of tumorigenesis, growth, invasion and metastatic spread. Extracellular vesicles, especially exosomes, released by primary tumors promote angiogenesis and cancer progression. However, the mechanism underlying the pro-angiogenic potency of cancer cell-...

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Detalles Bibliográficos
Autores principales: Han, Baoai, Zhang, He, Tian, Ruinan, Liu, Hui, Wang, Zhaosong, Wang, Zhiyong, Tian, Jianfei, Cui, Yanfen, Ren, Sixin, Zuo, Xiaoyan, Tian, Ran, Niu, Ruifang, Zhang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169374/
https://www.ncbi.nlm.nih.gov/pubmed/35673569
http://dx.doi.org/10.7150/thno.72404