Progesterone activates GPR126 to promote breast cancer development via the Gi pathway

GPR126 is a member of the adhesion G protein-coupled receptors (aGPCRs) that is essential for the normal development of diverse tissues, and its mutations are implicated in various pathological processes. Here, through screening 34 steroid hormones and their derivatives for cAMP production, we found...

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Detalles Bibliográficos
Autores principales: An, Wentao, Lin, Hui, Ma, Lijuan, Zhang, Chao, Zheng, Yuan, Cheng, Qiuxia, Ma, Chuanshun, Wu, Xiang, Zhang, Zihao, Zhong, Yani, Wang, Menghui, He, Dongfang, Yang, Zhao, Du, Lutao, Feng, Shiqing, Wang, Chuanxin, Yang, Fan, Xiao, Peng, Zhang, Pengju, Yu, Xiao, Sun, Jin-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169622/
https://www.ncbi.nlm.nih.gov/pubmed/35394864
http://dx.doi.org/10.1073/pnas.2117004119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169622/
https://www.ncbi.nlm.nih.gov/pubmed/35394864
http://dx.doi.org/10.1073/pnas.2117004119

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