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Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness
Collateral sensitivity is an evolutionary trade-off whereby acquisition of the adaptive phenotype of resistance to an antibiotic leads to the nonadaptive increased susceptibility to another. The feasibility of harnessing such a trade-off to design evolutionary-based approaches for treating bacterial...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169633/ https://www.ncbi.nlm.nih.gov/pubmed/35385351 http://dx.doi.org/10.1073/pnas.2109370119 |