Persistence of plasmids targeted by CRISPR interference in bacterial populations

CRISPR-Cas systems provide prokaryotes with an RNA-guided defense against foreign mobile genetic elements (MGEs) such as plasmids and viruses. A common mechanism by which MGEs avoid interference by CRISPR consists of acquisition of escape mutations in regions targeted by CRISPR. Here, using microbio...

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Detalles Bibliográficos
Autores principales: Mamontov, Viktor, Martynov, Alexander, Morozova, Natalia, Bukatin, Anton, Staroverov, Dmitry B., Lukyanov, Konstantin A., Ispolatov, Yaroslav, Semenova, Ekaterina, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169639/
https://www.ncbi.nlm.nih.gov/pubmed/35394860
http://dx.doi.org/10.1073/pnas.2114905119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169639/
https://www.ncbi.nlm.nih.gov/pubmed/35394860
http://dx.doi.org/10.1073/pnas.2114905119

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