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Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia

Enhancers integrate transcription factor signaling pathways that drive cell fate specification in the developing brain. We paired enhancer labeling and single-cell RNA-sequencing (scRNA-seq) to delineate and distinguish specification of neuronal lineages in mouse medial, lateral, and caudal ganglion...

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Detalles Bibliográficos
Autores principales: Su-Feher, Linda, Rubin, Anna N., Silberberg, Shanni N., Catta-Preta, Rinaldo, Lim, Kenneth J., Ypsilanti, Athena R., Zdilar, Iva, McGinnis, Christopher S., McKinsey, Gabriel L., Rubino, Thomas E., Hawrylycz, Michael J., Thompson, Carol, Gartner, Zev J., Puelles, Luis, Zeng, Hongkui, Rubenstein, John L. R., Nord, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169651/
https://www.ncbi.nlm.nih.gov/pubmed/35377797
http://dx.doi.org/10.1073/pnas.2108760119