Prenatal disruption of blood–brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation

Gestational maternal immune activation (MIA) in mice induces persistent brain microglial activation and a range of neuropathologies in the adult offspring. Although long-term phenotypes are well documented, how MIA in utero leads to persistent brain inflammation is not well understood. Here, we foun...

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Detalles Bibliográficos
Autores principales: Zhao, Qiuying, Dai, Weiye, Chen, Hui Yu, Jacobs, Russell E., Zlokovic, Berislav V., Lund, Brett T., Montagne, Axel, Bonnin, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169666/
https://www.ncbi.nlm.nih.gov/pubmed/35377817
http://dx.doi.org/10.1073/pnas.2113310119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169666/
https://www.ncbi.nlm.nih.gov/pubmed/35377817
http://dx.doi.org/10.1073/pnas.2113310119

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