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Prenatal disruption of blood–brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation
Gestational maternal immune activation (MIA) in mice induces persistent brain microglial activation and a range of neuropathologies in the adult offspring. Although long-term phenotypes are well documented, how MIA in utero leads to persistent brain inflammation is not well understood. Here, we foun...
Autores principales: | Zhao, Qiuying, Dai, Weiye, Chen, Hui Yu, Jacobs, Russell E., Zlokovic, Berislav V., Lund, Brett T., Montagne, Axel, Bonnin, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169666/ https://www.ncbi.nlm.nih.gov/pubmed/35377817 http://dx.doi.org/10.1073/pnas.2113310119 |
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