Cargando…

A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives

We identified the anti-Mullerian hormone (also known as Müllerian inhibiting substance or MIS) as an inhibitory hormone that induces long-term contraception in mammals. The type II receptor to this hormone, AMHR2 (also known as MISR2), represents a promising druggable target for the modulation of fe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yi, Wei, Lina, Meinsohn, Marie-Charlotte, Suliman, Rana, Chauvin, Maeva, Berstler, Jim, Hartland, Kate, Jensen, Mark M., Sicher, Natalie A., Nagykery, Nicholas, Donahoe, Patricia K., Pepin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169708/
https://www.ncbi.nlm.nih.gov/pubmed/35380904
http://dx.doi.org/10.1073/pnas.2122512119