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A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives
We identified the anti-Mullerian hormone (also known as Müllerian inhibiting substance or MIS) as an inhibitory hormone that induces long-term contraception in mammals. The type II receptor to this hormone, AMHR2 (also known as MISR2), represents a promising druggable target for the modulation of fe...
Autores principales: | Li, Yi, Wei, Lina, Meinsohn, Marie-Charlotte, Suliman, Rana, Chauvin, Maeva, Berstler, Jim, Hartland, Kate, Jensen, Mark M., Sicher, Natalie A., Nagykery, Nicholas, Donahoe, Patricia K., Pepin, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169708/ https://www.ncbi.nlm.nih.gov/pubmed/35380904 http://dx.doi.org/10.1073/pnas.2122512119 |
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