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Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis

The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune pathways that release inflammatory cytokines and growth factors such as tumor growth factor (TGF)β1 and induce aberrant extracellular matrix protein production. During the genesis of pulmonary fibrosis, resident...

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Detalles Bibliográficos
Autores principales: Singh, Abhalaxmi, Chakraborty, Sreeparna, Wong, Sing Wan, Hefner, Nicole A., Stuart, Andrew, Qadir, Abdul S., Mukhopadhyay, Amitabha, Bachmaier, Kurt, Shin, Jae-Won, Rehman, Jalees, Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169714/
https://www.ncbi.nlm.nih.gov/pubmed/35377803
http://dx.doi.org/10.1073/pnas.2121098119