Cargando…
Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis
The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune pathways that release inflammatory cytokines and growth factors such as tumor growth factor (TGF)β1 and induce aberrant extracellular matrix protein production. During the genesis of pulmonary fibrosis, resident...
Autores principales: | Singh, Abhalaxmi, Chakraborty, Sreeparna, Wong, Sing Wan, Hefner, Nicole A., Stuart, Andrew, Qadir, Abdul S., Mukhopadhyay, Amitabha, Bachmaier, Kurt, Shin, Jae-Won, Rehman, Jalees, Malik, Asrar B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169714/ https://www.ncbi.nlm.nih.gov/pubmed/35377803 http://dx.doi.org/10.1073/pnas.2121098119 |
Ejemplares similares
-
Albumin
Nanoparticle Endocytosing Subset of Neutrophils
for Precision Therapeutic Targeting of Inflammatory Tissue Injury
por: Bachmaier, Kurt, et al.
Publicado: (2022) -
Trained immunity of alveolar macrophages enhances injury resolution via KLF4-MERTK-mediated efferocytosis
por: Chakraborty, Sreeparna, et al.
Publicado: (2023) -
Interleukin-1RA Mitigates SARS-CoV-2–Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice
por: Xiong, Shiqin, et al.
Publicado: (2021) -
Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
por: Zhang, Fenghua, et al.
Publicado: (2020) -
Therapeutic Administration of the Chemokine CXCL1/KC Abrogates Autoimmune Inflammatory Heart Disease
por: Bachmaier, Kurt, et al.
Publicado: (2014)