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Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

Lymphatic filariasis is a vector-borne neglected tropical disease prioritized for global elimination. The filarial nematodes that cause the disease host a symbiotic bacterium, Wolbachia, which has been targeted using antibiotics, leading to cessation of parasite embryogenesis, waning of circulating...

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Detalles Bibliográficos
Autores principales: Quek, Shannon, Cook, Darren A. N., Wu, Yang, Marriott, Amy E., Steven, Andrew, Johnston, Kelly L., Ford, Louise, Archer, John, Hemingway, Janet, Ward, Stephen A., Wagstaff, Simon C., Turner, Joseph D., Taylor, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169722/
https://www.ncbi.nlm.nih.gov/pubmed/35377795
http://dx.doi.org/10.1073/pnas.2120003119