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rDNA array length is a major determinant of replicative lifespan in budding yeast

The complex processes and interactions that regulate aging and determine lifespan are not fully defined for any organism. Here, taking advantage of recent technological advances in studying aging in budding yeast, we discovered a previously unappreciated relationship between the number of copies of...

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Detalles Bibliográficos
Autores principales: Hotz, Manuel, Thayer, Nathaniel H., Hendrickson, David G., Schinski, Elizabeth L., Xu, Jun, Gottschling, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169770/
https://www.ncbi.nlm.nih.gov/pubmed/35394872
http://dx.doi.org/10.1073/pnas.2119593119