Cargando…
rDNA array length is a major determinant of replicative lifespan in budding yeast
The complex processes and interactions that regulate aging and determine lifespan are not fully defined for any organism. Here, taking advantage of recent technological advances in studying aging in budding yeast, we discovered a previously unappreciated relationship between the number of copies of...
Autores principales: | Hotz, Manuel, Thayer, Nathaniel H., Hendrickson, David G., Schinski, Elizabeth L., Xu, Jun, Gottschling, Daniel E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169770/ https://www.ncbi.nlm.nih.gov/pubmed/35394872 http://dx.doi.org/10.1073/pnas.2119593119 |
Ejemplares similares
-
Mitochondrial Tethers and Their Impact on Lifespan in Budding Yeast
por: Pernice, Wolfgang M., et al.
Publicado: (2018) -
DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding Yeast
por: Weinberger, Martin, et al.
Publicado: (2007) -
Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication
por: Shyian, Maksym, et al.
Publicado: (2016) -
Measuring Replicative Life Span in the Budding Yeast
por: Steffen, Kristan K., et al.
Publicado: (2009) -
The spatial arrangement of ORC binding modules determines the functionality of replication origins in budding yeast
por: Bolon, Yung-Tsi, et al.
Publicado: (2006)