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Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex hypomyelination

Major Depressive Disorder (MDD) is a chronic debilitating illness affecting yearly 300 million people worldwide. Oligodendrocyte-lineage cells have emerged as important neuromodulators in synaptic plasticity and crucial components of MDD pathophysiology. Using the repeated social defeat (RSDS) mouse...

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Detalles Bibliográficos
Autores principales: Kokkosis, Alexandros G., Madeira, Miguel M., Mullahy, Matthew R., Tsirka, Stella E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169792/
https://www.ncbi.nlm.nih.gov/pubmed/35301426
http://dx.doi.org/10.1038/s41380-022-01512-y