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Cryoelectron microscopy of Na(+),K(+)-ATPase in the two E2P states with and without cardiotonic steroids
Cryoelectron microscopy (cryo-EM) was applied to Na(+),K(+)-ATPase (NKA) to determine the structures of two E2P states, one (E2P(ATP)) formed by ATP and Mg(2+) in the forward reaction, and the other (E2P(Pi)) formed by inorganic phosphate (P(i)) and Mg(2+) in the backward reaction, with and without...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169807/ https://www.ncbi.nlm.nih.gov/pubmed/35380894 http://dx.doi.org/10.1073/pnas.2123226119 |