Cargando…

Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression

The size of the satellite cell pool is reduced in estradiol (E(2))-deficient female mice and humans. Here, we use a combination of in vivo and in vitro approaches to identify mechanisms, whereby E(2) deficiency impairs satellite cell maintenance. By measuring satellite cell numbers in mice at severa...

Descripción completa

Detalles Bibliográficos
Autores principales: Larson, Alexie A., Shams, Ahmed S., McMillin, Shawna L., Sullivan, Brian P., Vue, Cha, Roloff, Zachery A., Batchelor, Eric, Kyba, Michael, Lowe, Dawn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169829/
https://www.ncbi.nlm.nih.gov/pubmed/35442828
http://dx.doi.org/10.1152/ajpcell.00429.2021